TPO: Thyroid Peroxidase Antibody

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TPO: Thyroid Peroxidase Antibody


Dr. Bob’s Lab Testing Notes: This test is a continuation to help you on your path toward a healthier thyroid, and includes a brief review upon receiving the results. 


Thyroid Peroxidase Antibody


Autoantibodies to thyroid antigens can cause thyroid tissue injury that leads to transient hyperthyroidism and long-term hypothyroidism. 


Thyroid antibodies include antibody to thyroglobulin and microsomal proteins. 


Measurement of antimicrosomal antibodies is a more sensitive test for diagnosis of thyroiditis. Measurement of antimicrosomal antibodies is especially useful in confirming a diagnosis of subclinical hypothyroidism in patients with elevated serum TSH concentration and normal free T4 concentration. 


Between 5 and 25% of patients with high titer antimicrosomal antibodies convert to overt hypothyroidism each year. 


Antimicrosomal antibodies are almost always detectable in patients with Hashimoto thyroiditis, atopic thyroiditis, and postpartum thyroiditis. 


Antimicrosomal antibodies are also present in many cases of Graves disease. Antibody is seldom detectable in non-autoimmune thyroid diseases.


A purchase of this test includes a brief review with Dr. Bob. Scheduling will take place after ordering. 

Refund Policy: Due to the nature and integrity of our suppliers, all sales of testing services are final and non-refundable. Thank you.

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